GeneTex
United States (US)

CD4 antibody [LT4]

Cat No. GTX28361

Host Mouse
Clonality Monoclonal
Clone Name LT4
Isotype IgG1
Application IA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IA Assay dependent
Not tested in other applications.

Calculated MW

31.24 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.1 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent

Antigen Species

Human

Immunogen

Normal human blood lymphocytes

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CD4, CD4 molecule, CD4mut

Background

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]

Database

Research Area

Package List Price ($)
$ 219