GeneTex

  • Country / Location Selection

United States (US)

CD40 antibody [C40/1605]

Anti-CD40 antibody [C40/1605] used in IHC (Paraffin sections) (IHC-P). GTX34506
Anti-CD40 antibody [C40/1605] used in Flow cytometry (FACS). GTX34506
Anti-CD40 antibody [C40/1605] used in IHC (Paraffin sections) (IHC-P). GTX34506
Anti-CD40 antibody [C40/1605] used in IHC (Paraffin sections) (IHC-P). GTX34506

Cat. No. GTX34506

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 C40/1605

Isotype

 IgG1

Application

 ICC/IF, IHC-P, FACS

Reactivity

 Human
Package
100 μg ($529)
See all CD40 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
FACS 1-2μg/10⁶ cells

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human CD40 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Bp50 , CD40 , CD40 molecule , CDW40 , TNFRSF5 , p50

Cellular Localization

Cell membrane,Secreted

Background

This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014]

Database

Research Area

DATA IMAGES

Anti-CD40 antibody [C40/1605] used in IHC (Paraffin sections) (IHC-P). GTX34506

GTX34506 IHC-P Image

IHC-P analysis of human Hodgkin’s lymphoma tissue using GTX34506 CD40 antibody [C40/1605].

Anti-CD40 antibody [C40/1605] used in Flow cytometry (FACS). GTX34506

GTX34506 FACS Image

FACS analysis of U2OS cells using GTX34506 CD40 antibody [C40/1605].
Blue : Primary antibody
Red : Isotype control

Anti-CD40 antibody [C40/1605] used in IHC (Paraffin sections) (IHC-P). GTX34506

GTX34506 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX34506 CD40 antibody [C40/1605].

Anti-CD40 antibody [C40/1605] used in IHC (Paraffin sections) (IHC-P). GTX34506

GTX34506 IHC-P Image

IHC-P analysis of human spleen tissue using GTX34506 CD40 antibody [C40/1605].

REFERENCE

There are currently no references for CD40 antibody [C40/1605] (GTX34506). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for CD40 antibody [C40/1605] (GTX34506). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529