CD40L / CD154 antibody [MR1] (Biotin)

Cat. No. GTX01485-02
References 4
Cat. No.  GTX01485-02
Anti-CD40L / CD154 antibody [MR1] (Biotin) used in Flow cytometry (FCM). GTX01485-02
GTX01485-02 FCM Image

FACS analysis of mouse C57Bl/6 T cells (enriched from total splenocytes, with PMA and Ionomycin stimulation for 6 hrs) using GTX01485-02 CD40L / CD154 antibody [MR1] (Biotin).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)

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Anti-CD40L / CD154 antibody [MR1] (Biotin) used in Flow cytometry (FCM). GTX01485-02
  • Host
    Armenian Hamster
  • Clonality
    Monoclonal
  • Clone Name
    MR1
  • Isotype
    IgG
  • Applications
    FCM
  • Reactivity
    Mouse
Summary
The MR1 antibody is specific for mouse CD154, a 39 kD glycoprotein that is primarily expressed on activated T cells. CD154 (CD40 ligand, gp39) binds to CD40 expressed on antigen presenting cells and mediates important costimulatory functions between these cells. Signals generated via cognate interactions between CD154-CD40 on activated T and B cells are required for T-dependent B cell responses. The MR1 antibody is reported to block interaction of CD154 with CD40.
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