APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:1000-1:10000 |
Not tested in other applications.
Calculated MW
Product Note
This antibody was raised against human CD41 Extracellular domain.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the Extracellular domain of human CD41. The exact sequence is proprietary.
Purification
Affinity purified by Protein A.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
integrin subunit alpha 2b , BDPLT16 , BDPLT2 , CD41 , CD41B , GP2B , GPIIb , GT , GTA , HPA3 , PPP1R93
Cellular Localization
Membrane; Single-pass type I membrane protein
Background
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
Database
Research Area
DATA IMAGES
![Anti-CD41 antibody [HL2052] used in Western Blot (WB). GTX637956](/templates/default/js/lightbox/images/loading.gif "Anti-CD41 antibody [HL2052] used in Western Blot (WB). GTX637956")
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GTX637956 WB Image
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with CD41 antibody [HL2052] (GTX637956) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
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REFERENCE
There are currently no references for CD41 antibody [HL2052] (GTX637956). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD41 antibody [HL2052] (GTX637956). Be the first to share your experience with this product.
![Anti-CD41 antibody [HL2052] used in Western Blot (WB). GTX637956](/upload/website/prouct_img/small/GTX637956/GTX637956_44942_20230210_WB_TPM_watermark_23021401_394.webp "Anti-CD41 antibody [HL2052] used in Western Blot (WB). GTX637956")
![Anti-CD41 antibody [HL2052] used in Western Blot (WB). GTX637956](/upload/website/prouct_img/normal/GTX637956/GTX637956_44942_20230210_WB_TPM_watermark_23021401_394.webp "Anti-CD41 antibody [HL2052] used in Western Blot (WB). GTX637956")