*Optimal dilutions/concentrations should be determined by the researcher.
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.
Not tested in other applications.
The recognition of this antibody is dependent upon an intact CD41/61 complex.
PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Batch dependent (Please refer to the vial label for the specific concentration.)
Human platelet plasma membranes.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Integrin Subunit Alpha 2B , Bdplt16 , Bdplt2 , Cd41 , Cd41B , Gp2B , Gpiib , Gt , Gta , Hpa3 , Ppp1R93 , Itga2B
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
GTX76179 FACS Image
FACS analysis of human peripheral blood platelets using GTX76179 CD41 antibody [PM6/248] (PE).