APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes neuraminidase-sensitive epitope on CD43 (Leukosialin).
PROPERTIES
Form
Liquid
Buffer
TBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human T lymphocytes.
Purification
Purified IgG
Conjugation
Biotin
The reagent is free of unconjugated biotin.
RRID
AB_625667
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD43 , GALGP , GPL115 , LSN , SPN , sialophorin
Cellular Localization
Membrane
Background
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
Database
Research Area
DATA IMAGES
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GTX78288 FACS Image
FACS analysis of human peripheral blood using GTX78288 CD43 antibody [MEM-59] (Biotin).
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REFERENCE
There are currently no references for CD43 antibody [MEM-59] (Biotin) (GTX78288). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD43 antibody [MEM-59] (Biotin) (GTX78288). Be the first to share your experience with this product.