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CD43 antibody [MEM-59]

Anti-CD43 antibody [MEM-59] used in IHC (Paraffin sections) (IHC-P). GTX29088
Anti-CD43 antibody [MEM-59] used in Western Blot (WB). GTX29088

Cat. No. GTX29088

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-59

Isotype

 IgG1

Application

 WB, IHC-P, FACS, IP

Reactivity

 Human
Package
100 μg ($399)
See all CD43 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Product Note

This antibody recognizes neuraminidase-sensitive epitope on CD43 (Leukosialin).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human T lymphocytes.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD43 , GALGP , GPL115 , LSN , SPN , sialophorin

Cellular Localization

Membrane

Background

This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

Database

Research Area

DATA IMAGES

Anti-CD43 antibody [MEM-59] used in IHC (Paraffin sections) (IHC-P). GTX29088

GTX29088 IHC-P Image

IHC-P analysis of human spleen tissue using GTX29088 CD43 antibody [MEM-59].

Anti-CD43 antibody [MEM-59] used in Western Blot (WB). GTX29088

GTX29088 WB Image

WB analysis of isolated peripheral blood lymphocytes (non-reducing) using GTX29088 CD43 antibody [MEM-59].
Lane 1: human PBL lysate
Lane 2 : dog PBL lysate
Lane 3 : pig PBL lysate

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399