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CD43 antibody [MT1]

Anti-CD43 antibody [MT1] used in IHC (Paraffin sections) (IHC-P). GTX01920

Cat. No. GTX01920

Host

Mouse

Clonality

Monoclonal

Clone Name

MT1

Isotype

IgG1

Application

IHC-P, IHC-Fr

Reactivity

Human
Package
500 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:40
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Human lymphocytes.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sialophorin , CD43 , GALGP , GPL115 , LSN

Cellular Localization

Membrane

Background

This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

Database

Research Area

DATA IMAGES

Anti-CD43 antibody [MT1] used in IHC (Paraffin sections) (IHC-P). GTX01920

GTX01920 IHC-P Image

IHC-P analysis of diffuse large B cell lymphoma tissue using GTX01920 CD43 antibody [MT1]. Note the intense staining of malignant CD43: clone MT1

REFERENCE

There are currently no references for CD43 antibody [MT1] (GTX01920). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 399