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CD44 antibody [IM7] (Biotin)

Anti-CD44 antibody [IM7] (Biotin) used in Flow cytometry (FACS). GTX19629

Cat No. GTX19629

Host

Rat

Clonality

Monoclonal

Clone Name

IM7

Isotype

IgG2b

Application

IHC-Fr, FACS, IP

Reactivity

Human, Bovine, Cat, Dog, Pig, Horse
Package
125 μg ($379)

APPLICATION

Application Note

FACS: Use 1μg for 10^6 cells. IHC-Fr (acetone fixed): Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

82 kDa. ( Note )

Product Note

Recognizes all isoforms of the Pgp-1 cell surface glycoprotein. The CD44 is present on B-cells, monocytes, macrophages and certain subsets of thymocytes and peripheral T-cells. Mice with the Ly-24.1 allotype have high densities of CD44+ T-cells, while Ly-24.2 strains are low expressors.

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.2, 1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Unfortunately, this information is considered to be commercially sensitive

Purification

Protein A purified

Conjugation

Biotin

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD44 molecule (Indian blood group) , CDW44 , CSPG8 , ECMR-III , HCELL , HUTCH-I , IN , LHR , MC56 , MDU2 , MDU3 , MIC4 , Pgp1

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD44 antibody [IM7] (Biotin) used in Flow cytometry (FACS). GTX19629

GTX19629 FACS Image

Staining of C57 splenocytes with Anti-Mouse CD44: Biotin (purple histogram) or Rat IgG2b Isotype Control: Biotin (open histogram) followed by UltraAvidin: PE

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 379