CD44 antibody
Cat. No. GTX102111
Cat. No. GTX102111
This CD44 antibody (GTX102111) is a rabbit polyclonal antibody validated for detection of CD44 by WB, ICC/IF, IHC-P, IHC-Fr, IP, and LCI. Reactivity has been shown in Human, Rat, and Rabbit. This product is cited in 52 published studies. Knockout/knockdown validation supports antibody specificity.
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HostRabbit
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ClonalityPolyclonal
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IsotypeIgG
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ApplicationsWB ICC/IF IHC-P IHC-Fr IP LCI
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ReactivityHuman, Rat, Rabbit
Summary
CD44 is an 82kDa multifunctional transmembrane glycoprotein involved in cell migration, proliferation, differentiation, and signaling pathways that mediate cell survival. It is involved in many malignancies as well as being recognized as a cancer stem cell marker. Importantly, it is expressed in leukocytes and is a marker of leukemia-initiating cells, being found to be critical in the pathogenesis of T cell acute lymphoblastic leukemia.