APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
1/200 |
1/400-1/500 |
1/50-1/200 |
Note :
IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
|
Not tested in other applications.
Product Note
This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of human CD44.
Purification
Purified IgG
Conjugation
Unconjugated
RRID
AB_366728
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
LHR Antibody , HUTCH-I Antibody , CDW44 Antibody , CD44 Antibody , ECMR-III Antibody , MDU2 Antibody , CSPG8 Antibody , Pgp1 Antibody , IN Antibody , MIC4 Antibody , MDU3 Antibody , MC56 Antibody , CD44 molecule (Indian blood group) Antibody , HCELL Antibody
Background
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Research Area
DATA IMAGES
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GTX75291 IHC-P Image
IHC-P analysis of human breast cancer tissue using GTX75291 CD44v6 antibody [VFF-7].
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GTX75291 IHC-P Image
IHC-P analysis of human breast cancer tissue using GTX75291 CD44v6 antibody [VFF-7].
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REFERENCE
There are currently no references for CD44v6 antibody [VFF-7] (GTX75291). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD44v6 antibody [VFF-7] (GTX75291). Be the first to share your experience with this product.