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CD44v7/8 antibody [VFF-17]

Cat. No. GTX75295

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 VFF-17

Isotype

 IgG2b

Application

 IHC-P, IHC-Fr, FACS

Reactivity

 Human
Package
100 μg ($499)
See all CD44v7/8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1/100
IHC-Fr 1/100-1/1,000
FACS 1/10-1/100

Note :

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Product Note

This antibody recognizes an epitope encoded by exons v7-v8 on the variant portion of human CD44.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_366732

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LHR Antibody , HUTCH-I Antibody , CDW44 Antibody , CD44 Antibody , ECMR-III Antibody , MDU2 Antibody , CSPG8 Antibody , Pgp1 Antibody , IN Antibody , MIC4 Antibody , MDU3 Antibody , MC56 Antibody , CD44 molecule (Indian blood group) Antibody , HCELL Antibody

Background

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 499
Custom Conjugations