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CD44v7 antibody [VFF-9]

Cat No. GTX75293

Host

Mouse

Clonality

Monoclonal

Clone Name

VFF-9

Isotype

IgG1

Application

WB, IHC-P, IHC-Fr, FACS

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P 1/50
IHC-Fr 1/50
FACS 1/50

Note :

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Not tested in other applications.

Specificity/Sensitivity

This antibody recognizes an epitope encoded by exon v7 on the variant portion of human CD44.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.01% Thiomersal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of human CD44.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

LHR Antibody , HUTCH-I Antibody , CDW44 Antibody , CD44 Antibody , ECMR-III Antibody , MDU2 Antibody , CSPG8 Antibody , Pgp1 Antibody , IN Antibody , MIC4 Antibody , MDU3 Antibody , MC56 Antibody , CD44 molecule (Indian blood group) Antibody , HCELL Antibody

Background

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

There are currently no references for CD44v7 antibody [VFF-9] (GTX75293). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 339