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CD45 antibody [HI30]

Anti-CD45 antibody [HI30] used in Flow cytometry (FACS). GTX00526

Cat No. GTX00526

Host

Mouse

Clonality

Monoclonal

Clone Name

HI30

Isotype

IgG1

Application

WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP

Reactivity

Human, Primate
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

147 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes all isoforms of human CD45 antigen (Leukocyte Common Antigen).

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-CD45 antibody [HI30] used in Flow cytometry (FACS). GTX00526

GTX00526 FACS Image

FACS analysis of human peripheral blood using GTX00526 CD45 antibody [HI30].

REFERENCE

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REVIEW

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Package List Price ($)
$ 319