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CD45 antibody [IH1]

Cat. No. GTX82980

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IH1

Isotype

 IgG

Application

 ICC/IF, IHC-Fr, IP

Reactivity

 Human
Package
500 μg ($399)
See all CD45 products

APPLICATION

Application Note

For IF: Use at a concentration of 5-20μg/ml. For IP: Use at a concentration of 5-20μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Positive Control

H201

Product Note

Detects all isoforms (180-220 kDa)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Guinea pig

Immunogen

Leukaemic lymphocytes from guinea pig

Purification

Protein A affinity purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
Custom Conjugations