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CD45 antibody [IHC045]

Anti-CD45 antibody [IHC045] used in IHC (Paraffin sections) (IHC-P). GTX57203

Cat. No. GTX57203

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IHC045

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($399)
See all CD45 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Calculated MW

147 kDa. ( Note )

Positive Control

Tonsil, Lymph Node, Lymphoma

PROPERTIES

Form

Liquid

Buffer

Tris buffer, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human CD45 (LCA) protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Protein Tyrosine Phosphatase, Receptor Type C , B220 , Cd45 , Cd45R , Gp180 , L-Ca , Lca , Ly5 , T200 , Ptprc

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Research Area

DATA IMAGES

Anti-CD45 antibody [IHC045] used in IHC (Paraffin sections) (IHC-P). GTX57203

GTX57203 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX57203 CD45 antibody [IHC045]

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399