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CD45 antibody [X16/99]

Anti-CD45 antibody [X16/99] used in IHC (Paraffin sections) (IHC-P). GTX01850

Cat. No. GTX01850

Host

Mouse

Clonality

Monoclonal

Clone Name

X16/99

Isotype

IgG1

Application

IHC-P, IHC-Fr

Reactivity

Human
Package
500 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:40
IHC-Fr Assay dependent

Note :

IHC-P
Heat Induced Epitope Retrieval (HIER) was performed in Retrieval Solution pH 6

Not tested in other applications.

Calculated MW

147 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Peripheral blood cells from a patient with T cell lymphoma.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-CD45 antibody [X16/99] used in IHC (Paraffin sections) (IHC-P). GTX01850

GTX01850 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX01850 CD45 antibody [X16/99].

REFERENCE

There are currently no references for CD45 antibody [X16/99] (GTX01850). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD45 antibody [X16/99] (GTX01850). Be the first to share your experience with this product.
Package List Price ($)
$ 399