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CD45RA antibody [F8-11-13] (PE)

Cat No. GTX76598

Host

Mouse

Clonality

Monoclonal

Clone Name

F8-11-13

Isotype

IgG1

Application

FACS

Reactivity

Human, Rhesus Monkey
Package
100 test ($409)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS Neat

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.

Not tested in other applications.

Specificity/Sensitivity

This antibody reacts with the high molecular weight form of the leucocyte common antigen (LCA) expressed by B lymphocytes and a subset of T lymphocytes.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human T lymphocytes

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD45 Antibody , LY5 Antibody , T200 Antibody , L-CA Antibody , PTPRC Antibody , LCA Antibody , CD45R Antibody , protein tyrosine phosphatase, receptor type, C Antibody , B220 Antibody , GP180 Antibody

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409