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CD45RA antibody [MEM-56] (Biotin)

Anti-CD45RA antibody [MEM-56] (Biotin) used in Flow cytometry (FACS). GTX78297

Cat. No. GTX78297

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-56

Isotype

 IgG2b

Application

 WB, IHC-P, FACS, IP

Reactivity

 Human
Package
100 μg ($399)
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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

147 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

TBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human thymocytes and T lymphocytes.

Purification

Purified IgG

Conjugation

Biotin
The reagent is free of unconjugated biotin.

RRID

AB_625661

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-CD45RA antibody [MEM-56] (Biotin) used in Flow cytometry (FACS). GTX78297

GTX78297 FACS Image

FACS analysis of human peripheral blood using GTX78297 CD45RA antibody [MEM-56] (Biotin).

REFERENCE

Clone Reference

Wu F et al. Inflammation 2019; (Epub) Cellular Inflammatory Response of the Spleen After Acute Spinal Cord Injury in Rat.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399