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CD45RA antibody [MEM-56]

Anti-CD45RA antibody [MEM-56] used in Western Blot (WB). GTX28217
Anti-CD45RA antibody [MEM-56] used in IHC (Paraffin sections) (IHC-P). GTX28217

Cat. No. GTX28217

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-56

Isotype

 IgG2b

Application

 WB, IHC-P, FACS, IP, MS

Reactivity

 Human, Rat
Package
100 μg ($399)
See all CD45RA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
FACS Assay dependent
IP Assay dependent
MS Assay dependent
Not tested in other applications.

Calculated MW

147 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human thymocytes and T lymphocytes.

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_366664

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-CD45RA antibody [MEM-56] used in Western Blot (WB). GTX28217

GTX28217 WB Image

WB analysis of HUT-78 cell lysate using GTX28217 CD45RA antibody [MEM-56].
Lane 1 : positive control anti-human CD45 antibody
Lane 2 : GTX28217 (non-reducing cell lysate)
Lane 3 : GTX28217 (reducing cell lysate)

Anti-CD45RA antibody [MEM-56] used in IHC (Paraffin sections) (IHC-P). GTX28217

GTX28217 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX28217 CD45RA antibody [MEM-56].
Diultion : 5μg/ml

REFERENCE

Application Reference

Wu F et al. Inflammation 2019; (Epub) Cellular Inflammatory Response of the Spleen After Acute Spinal Cord Injury in Rat.
Application : FACS
Reactivity : Rat
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399