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CD45RB antibody [MEM-55]

Anti-CD45RB antibody [MEM-55] used in Flow cytometry (FACS). GTX74645

Cat. No. GTX74645

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-55

Isotype

 IgG1

Application

 IHC-P, IHC-Fr, FACS, IP

Reactivity

 Human, Monkey, Rhesus Monkey
Package
200 μg ($459)
See all CD45RB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1/50-1/200
IHC-Fr Assay dependent
FACS 1/50-1/100
IP Assay dependent

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Product Note

This antibody recognizes the isoform of CD45 encoded by exon B.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_366717

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD45 Antibody , LY5 Antibody , T200 Antibody , L-CA Antibody , PTPRC Antibody , LCA Antibody , CD45R Antibody , protein tyrosine phosphatase, receptor type, C Antibody , B220 Antibody , GP180 Antibody

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Research Area

DATA IMAGES

Anti-CD45RB antibody [MEM-55] used in Flow cytometry (FACS). GTX74645

GTX74645 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX74645 CD45RB antibody [MEM-55].

REFERENCE

Clone Reference

Chopra H et al. Blood Cells Mol Dis 2021; 86:102487 CD133+CD34+ cells can give rise to EPCs: A comparative rabbit and human study.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459