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CD46 antibody [JB25-49]

Recombinant antibody
Anti-CD46 antibody [JB25-49] used in Western Blot (WB). GTX01058
Anti-CD46 antibody [JB25-49] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01058
Anti-CD46 antibody [JB25-49] used in IHC (Paraffin sections) (IHC-P). GTX01058
Anti-CD46 antibody [JB25-49] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01058
Anti-CD46 antibody [JB25-49] used in IHC (Paraffin sections) (IHC-P). GTX01058
Anti-CD46 antibody [JB25-49] used in IHC (Paraffin sections) (IHC-P). GTX01058
Anti-CD46 antibody [JB25-49] used in IHC (Paraffin sections) (IHC-P). GTX01058

Cat No. GTX01058

Host

Rabbit

Clonality

Monoclonal

Clone Name

JB25-49

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Rat
Package
100 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000-1:5000
ICC/IF 1:50-1:200
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Observed MW

56-66 kDa. The observed M.W. is based on the following publication. PMID: 22293503

PROPERTIES

Form

Liquid

Buffer

1x TBS (pH7.4), 1% BSA, 40% glycerol, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD46 molecule , AHUS2 , CD46 , MCP , MIC10 , TLX , TRA2.10

Cellular Localization

Cytoplasmic vesicle,Secretory vesicle,Acrosome inner membrane

Background

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-CD46 antibody [JB25-49] used in Western Blot (WB). GTX01058

GTX01058 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with CD46 antibody [JB25-49] (GTX01058) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
The observed M.W. is based on the publication: PMID: 22293503

Anti-CD46 antibody [JB25-49] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01058

GTX01058 ICC/IF Image

ICC/IF analysis of PFA-fixed HUVEC cells using GTX01058 CD46 antibody [JB25-49].
Green : primary antibody
Blue : DAPI
Permeabilization : 0.25% Triton X-100 in PBS

Anti-CD46 antibody [JB25-49] used in IHC (Paraffin sections) (IHC-P). GTX01058

GTX01058 IHC-P Image

IHC-P analysis of human placenta tissue section using GTX01058 CD46 antibody [JB25-49].

Anti-CD46 antibody [JB25-49] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01058

GTX01058 ICC/IF Image

ICC/IF analysis of PFA-fixed PC-3M cells using GTX01058 CD46 antibody [JB25-49].
Green : primary antibody
Blue : DAPI
Permeabilization : 0.25% Triton X-100 in PBS

Anti-CD46 antibody [JB25-49] used in IHC (Paraffin sections) (IHC-P). GTX01058

GTX01058 IHC-P Image

IHC-P analysis of rat kidney tissue section using GTX01058 CD46 antibody [JB25-49].

Anti-CD46 antibody [JB25-49] used in IHC (Paraffin sections) (IHC-P). GTX01058

GTX01058 IHC-P Image

IHC-P analysis of human breast tissue section using GTX01058 CD46 antibody [JB25-49].

Anti-CD46 antibody [JB25-49] used in IHC (Paraffin sections) (IHC-P). GTX01058

GTX01058 IHC-P Image

IHC-P analysis of human colon cancer tissue section using GTX01058 CD46 antibody [JB25-49].

REFERENCE

There are currently no references for CD46 antibody [JB25-49] (GTX01058). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD46 antibody [JB25-49] (GTX01058). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 369