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CD46 antibody [MEM-258] (FITC)

Anti-CD46 antibody [MEM-258] (FITC) used in Flow cytometry (FACS). GTX75834

Cat No. GTX75834

Host

Mouse

Clonality

Monoclonal

Clone Name

MEM-258

Isotype

IgG1

Application

FACS

Reactivity

Human, Bovine
Package
100 test ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein).

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

HPB-ALL human T cell line

Purification

Purified by size-exclusion chromatography

Conjugation

Fluorescein isothiocyanate (FITC)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AHUS2 , CD46 , CD46 molecule , MCP , MIC10 , TLX , TRA2.10

Cellular Localization

Cytoplasmic vesicle,Secretory vesicle,Acrosome inner membrane

Background

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-CD46 antibody [MEM-258] (FITC) used in Flow cytometry (FACS). GTX75834

GTX75834 FACS Image

FACS analysis of human peripheral blood using GTX75834 CD46 antibody [MEM-258] (FITC).

REFERENCE

There are currently no references for CD46 antibody [MEM-258] (FITC) (GTX75834). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD46 antibody [MEM-258] (FITC) (GTX75834). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329