GeneTex
United States (US)

CD57 antibody [SPM527]

GTX34528_20170712_IHC-P_18121410_934.jpg

Cat No. GTX34528

Host Mouse
Clonality Monoclonal
Clone Name SPM527
Isotype IgM
Application IHC-P
Reactivity Human
APPLICATION

Application Note

IHC-P:2-4ug/ml for 30 minutes at RT.

Calculated MW

38 kDa. ( Note )

Specificity/Sensitivity

Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
PROPERTIES

Form

Liquid

Buffer

Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Human peripheral blood mononuclear cells

Purification

Ab purified from Bioreactor Concentrate

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Beta-1,3-Glucuronyltransferase 1,Cd57,Glcatp,Glcuatp,Hnk1,Leu7,Nk-1,Nk1,B3Gat1

Background

The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX34528_20170712_IHC-P_18121410_934.jpg

GTX34528 IHC-P Image

Formalin-fixed, paraffin-embedded human Tonsil stained with CD57 Monoclonal Antibody (SPM527).

Package List Price ($)
$ 329