APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
Assay dependent |
Note :
FACS
using 1.0 x 10⁶ cells
|
Not tested in other applications.
Calculated MW
Product Note
Recognizes a (Mr 110kDa) carbohydrate molecule on myeloid cells. This surface antigen is associated withmyelin-associated glycoprotein (MAG).(1) This antibody blocks binding of HNK-1 (Leu. 7) antibody.(3)The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on asubset of natural killer cells (60% ) and on a subset of T-lymphocytes. This carbohydrate is also present onN-CAM in the nervous system.
PROPERTIES
Form
Liquid
Buffer
0.01M PBS pH7.4, 1mg/ml BSA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.10 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Cat unfixed cortical homogenate area 17.
Purification
Protein A purified
From tissue culture supernatant
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
beta-1,3-glucuronyltransferase 1 , CD57 , GLCATP , GLCUATP , HNK1 , LEU7 , NK-1 , NK1
Cellular Localization
Secreted , Endoplasmic reticulum membrane
Background
The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for CD57 antibody [VC1.1] (GTX44176). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD57 antibody [VC1.1] (GTX44176). Be the first to share your experience with this product.