GeneTex

  • Country / Location Selection

United States (US)

CD57 antibody [VC1.1]

Cat. No. GTX44176

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 VC1.1

Isotype

 IgM

Application

 WB, IHC-P, FACS

Reactivity

 Human
Package
200 μg ($489)
See all CD57 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
FACS Assay dependent

Note :

FACS
using 1.0 x 10⁶ cells
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Product Note

Recognizes a (Mr 110kDa) carbohydrate molecule on myeloid cells. This surface antigen is associated withmyelin-associated glycoprotein (MAG).(1) This antibody blocks binding of HNK-1 (Leu. 7) antibody.(3)The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on asubset of natural killer cells (60% ) and on a subset of T-lymphocytes. This carbohydrate is also present onN-CAM in the nervous system.

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.4, 1mg/ml BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.10 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Cat unfixed cortical homogenate area 17.

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

beta-1,3-glucuronyltransferase 1 , CD57 , GLCATP , GLCUATP , HNK1 , LEU7 , NK-1 , NK1

Cellular Localization

Secreted , Endoplasmic reticulum membrane

Background

The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for CD57 antibody [VC1.1] (GTX44176). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for CD57 antibody [VC1.1] (GTX44176). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 489