GeneTex
United States (US)

CD59 antibody

GTX53909_20180530_WB_18121410_692.jpg
GTX53909_20180530_IHC-P_18121410_290.jpg
GTX53909_20180530_IHC-P_1_18121410_209.jpg

Cat No. GTX53909

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

14 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant protein of human CD59

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

P1820 Antibody , MSK21 Antibody , MIN2 Antibody , MIN1 Antibody , G344 Antibody , MAC IP Antibody , EL32 Antibody , MACIF Antibody , EJ30 Antibody , MIRL Antibody , MIC11 Antibody , HRF20 Antibody , MIN3 Antibody , MEM43 Antibody , EJ16 Antibody , 1F5 Antibody , 16.3A5 Antibody

Background

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX53909_20180530_WB_18121410_692.jpg

GTX53909 WB Image

WB analysis of various samples using GTX53909 CD59 antibody.The signal was developed with ECL plus-Enhanced.
Dilution : 1:500
Loading : 25μg per lane

GTX53909_20180530_IHC-P_18121410_290.jpg

GTX53909 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX53909 CD59 antibody.

GTX53909_20180530_IHC-P_1_18121410_209.jpg

GTX53909 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX53909 CD59 antibody.

Package List Price ($)
$ 319