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CD59 antibody

Anti-CD59 antibody used in IHC (Paraffin sections) (IHC-P). GTX53909
Anti-CD59 antibody used in Western Blot (WB). GTX53909
Anti-CD59 antibody used in IHC (Paraffin sections) (IHC-P). GTX53909
Anti-CD59 antibody used in IHC (Paraffin sections) (IHC-P). GTX53909

Cat No. GTX53909

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:2000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

14 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein of human CD59

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD59 molecule (CD59 blood group) , 16.3A5 , 1F5 , EJ16 , EJ30 , EL32 , G344 , HRF-20 , HRF20 , MAC-IP , MACIF , MEM43 , MIC11 , MIN1 , MIN2 , MIN3 , MIRL , MSK21 , p18-20

Cellular Localization

Secreted

Background

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD59 antibody used in IHC (Paraffin sections) (IHC-P). GTX53909

GTX53909 IHC-P Image

IHC-P analysis of rat heart tissue using GTX53909 CD59 antibody.
Dilution : 1:100

Anti-CD59 antibody used in Western Blot (WB). GTX53909

GTX53909 WB Image

WB analysis of various sample lysates using GTX53909 CD59 antibody. The signal was developed with ECL plus-Enhanced.
Loading : 25ug per lane
Dilution : 1:500

Anti-CD59 antibody used in IHC (Paraffin sections) (IHC-P). GTX53909

GTX53909 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX53909 CD59 antibody.

Anti-CD59 antibody used in IHC (Paraffin sections) (IHC-P). GTX53909

GTX53909 IHC-P Image

IHC-P analysis of human lung cancer tissue using GTX53909 CD59 antibody.
Dilution : 1:100

REFERENCE

There are currently no references for CD59 antibody (GTX53909). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf