GeneTex

  • Country / Location Selection

United States (US)

CD62L antibody [MEL-14] (FITC)

Anti-CD62L antibody [MEL-14] (FITC) used in Flow cytometry (FACS). GTX80035

Cat. No. GTX80035

Host

 Rat

Clonality

 Monoclonal

Clone Name

 Mel-14

Isotype

 IgG3a

Application

 FACS

Reactivity

 Mouse
Package
100 μg ($339)
See all CD62L products
PRODUCT

Summary

The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin αfamily of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

C3H/eb mouse B cell lymphoma 38C-13

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Fluorescein isothiocyanate (FITC)

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

selectin, lymphocyte , AI528707 , CD62L , L-selectin , LECAM-1 , Lnhr , Ly-22 , Ly-m22 , Lyam-1 , Lyam1

Cellular Localization

Cell membrane

Database

Research Area

DATA IMAGES

Anti-CD62L antibody [MEL-14] (FITC) used in Flow cytometry (FACS). GTX80035

GTX80035 FACS Image

FACS analysis of C57Bl/6 splenocytes using GTX80035 CD62L antibody [MEL-14] (FITC).
Solid line : Primary antibody
Dashed line : FITC rat IgG2a isotype control
Antibody amount : 0.25 μg

REFERENCE

There are currently no references for CD62L antibody [MEL-14] (FITC) (GTX80035). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for CD62L antibody [MEL-14] (FITC) (GTX80035). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339