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CD63 antibody [MEM-259]

Anti-CD63 antibody [MEM-259] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX28219
Anti-CD63 antibody [MEM-259] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX28219
Anti-CD63 antibody [MEM-259] used in Flow cytometry (FACS). GTX28219
Anti-CD63 antibody [MEM-259] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX28219

Cat. No. GTX28219

Reference 6

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-259

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, FACS, IP

Reactivity

 Human
Package
100 μg ($399)
See all CD63 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 10 μg/ml
IHC-P 10 μg/ml
FACS 2 μg/ml
IP Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

HPB-ALL T cell line

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_374496

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD63 , CD63 molecule , LAMP3 , ME491 , MLA1 , OMA81H , TSPAN30

Cellular Localization

Cell membrane,Lysosome membrane,Late endosome membrane,Endosome,Multivesicular body,Melanosome

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

Database

Research Area

DATA IMAGES

Anti-CD63 antibody [MEM-259] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX28219

GTX28219 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX28219 CD63 antibody [MEM-259].
Green : Primary antibody
Red : Actin
Blue : DAPI

Anti-CD63 antibody [MEM-259] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX28219

GTX28219 ICC/IF Image

ICC/IF analysis of human primary fibroblasts using GTX28219 CD63 antibody [MEM-259].
Green : Primary antibody
Red : Actin
Blue : DAPI

Anti-CD63 antibody [MEM-259] used in Flow cytometry (FACS). GTX28219

GTX28219 FACS Image

FACS analysis of IgE-activated peripheral blood using GTX28219 CD63 antibody [MEM-259].

Anti-CD63 antibody [MEM-259] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX28219

GTX28219 ICC/IF Image

ICC/IF analysis of human skin fibroblasts using GTX28219 CD63 antibody [MEM-259].
Green : Primary antibody
Red : Transferrin
Blue : DAPI

REFERENCE

Application Reference

Cheng Zhang et al. J Extracell Vesicles 2022; 11 (4) : e12209 Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer.
Peng X et al. J Exp Clin Cancer Res 2021; 40 (1) : 183 LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation.
Application : ICC/IF
Reactivity : Human
Peng X et al. Biochim Biophys Acta Mol Cell Res 2021; 1868 (1) : 118857 IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells.
Application : WB, ICC/IF
Reactivity : Human
Yang L et al. Mol Cancer 2019; 18 (1) : 78 Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma.
Raulf N et al. Eur J Cancer 2018; 102 : 52-68 Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers.
Application : WB
Reactivity : Human
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399