*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
The antibody MEM-259 reacts with CD63 (Melanoma 1 antigen), a 40-60 kDa glycoprotein (tetraspans family, TM4SF). CD63 is translocated to the cell surface upon activation of platelets, endothelial cells, and granulocytes (activation marker); it is also expressed on monocytes/macrophages and endothelium.
Phosphate buffered saline pH 7.4 containing 15mM sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Tissue / cell preparation (Human). (T cell line HPB-ALL)
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
LAMP-3, ME491, MLA1, OMA81H, TSPAN30
CD63 is intracellular lysosomal/endosomal/granule protein that is translocated to cell surface upon activation of platelets, endothelial cells, and granulocytes (activation marker). CD63 is also expressed on monocytes/macrophages and endothelium. Its cellular function has not been exactly elucidated. CD63 is thought to be associated with the early stages of melanoma tumor progression (in regulation of motility and adhesion of melanoma cells).