GeneTex

  • Country / Location Selection

United States (US)

CD63 antibody

Anti-CD63 antibody used in Western Blot (WB). GTX37555
Anti-CD63 antibody used in IHC (Paraffin sections) (IHC-P). GTX37555
Anti-CD63 antibody used in IHC (Paraffin sections) (IHC-P). GTX37555
Anti-CD63 antibody used in IHC (Paraffin sections) (IHC-P). GTX37555

Cat. No. GTX37555

Reference 5

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Mouse, Rat
Package
50 μg ($399)
See all CD63 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:100-1000
IHC-P 1:100-500 (based on 0.5 mg/ml)
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human CD63.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_11175429

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD63 molecule , LAMP-3 , ME491 , MLA1 , OMA81H , TSPAN30

Cellular Localization

Cell membrane,Lysosome membrane

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

Database

Research Area

DATA IMAGES

Anti-CD63 antibody used in Western Blot (WB). GTX37555

GTX37555 WB Image

WB analysis of mouse heart (Lane 1), rat kidney (Lane 2), mouse spleen (Lane 3), rat thyroid (Lane 4) lysates using GTX37555 CD63 antibody.
Dilution : 1μg/ml

Anti-CD63 antibody used in IHC (Paraffin sections) (IHC-P). GTX37555

GTX37555 IHC-P Image

IHC-P analysis of mouse lymph node tissue using GTX37555 CD63 antibody.
Dilution : 2.5μg/ml

Anti-CD63 antibody used in IHC (Paraffin sections) (IHC-P). GTX37555

GTX37555 IHC-P Image

IHC-P analysis of mouse lymph node tissue using GTX37555 CD63 antibody.
Dilution : 2.5μg/ml

Anti-CD63 antibody used in IHC (Paraffin sections) (IHC-P). GTX37555

GTX37555 IHC-P Image

The data was published in the journal Biosci Rep in 2018. PMID: 29884767

REFERENCE

Application Reference

Zhang B et al. Oxid Med Cell Longev 2022; 2022 : 8215842 Exosomal miR-27b-3p Derived from Hypoxic Cardiac Microvascular Endothelial Cells Alleviates Rat Myocardial Ischemia/Reperfusion Injury through Inhibiting Oxidative Stress-Induced Pyroptosis via Foxo1/GSDMD Signaling.
Application : WB
Reactivity : Rat
Povero D et al. JCI Insight 2019; 5 Human induced pluripotent stem cell-derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis.
Lv C et al. Biosci Rep 2018; (Epub) MicroRNA-21 in extracellular vesicles contributes to the growth of fertilized eggs and embryo development in mice.
Application : IHC-P
Reactivity : Mouse
Jong AY et al. J Extracell Vesicles 2017; 6 (1) : 1294368 Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells.
Fornari F et al. PLoS One 2015; 10 (10) : e0141448 Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC.
Submit a Reference

REVIEW

There are currently no reviews for CD63 antibody (GTX37555). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399