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CD64 antibody [10.1] (PE-Cy7)

Cat. No. GTX00467-10

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10.1

Isotype

 IgG1

Application

 FACS

Reactivity

 Human, Primate
Package
100 test ($319)
See all CD64 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Product Note

This antibody recognizes alpha subunit of CD64/FcgammaRI.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rheumatoid synovial fluid cells and fibronectin purified human monocytes

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin-Cyanine7 (PE-Cy7)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

TARGET

Synonyms

CD64 , CD64A , FCGR1A , FCRI , Fc fragment of IgG receptor Ia , IGFR1

Cellular Localization

Cell membrane

Background

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Clone Reference

Yun-Jong Park et al. PLoS Pathog 2022; 18 (4):e1010468 D-dimer and CoV-2 spike-immune complexes contribute to the production of PGE2 and proinflammatory cytokines in monocytes.
Richards JO et al. Mol Cancer Ther 2008; 7 (8):2517-27 Optimization of antibody binding to FcgammaRIIa enhances macrophage phagocytosis of tumor cells.
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319