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CD66e antibody[CEA31]

Cat. No. GTX01652

Reference 5

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CEA31

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($399)
See all CD66e products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Pretreatment of deparaffinized tissue with heat-induced epitope retrieval or enzymatic retrieval is recommended.
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

Positive Control

Colon carcinoma

Product Note

Clone CEA31 has a high affinity for CEA and shows no detectable reactivity to nonspecific cross-reacting antigen (NCA), biliary glycoprotein (BGP) and human polymorphonuclear leucocytes.

PROPERTIES

Form

Liquid

Buffer

Tris-HCl, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human colon carcinoma extract

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

carcinoembryonic antigen related cell adhesion molecule 5 , CD66e , CEA

Cellular Localization

Cell membrane , Apical cell membrane , Cell surface

Background

This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

Database

Research Area

REFERENCE

Clone Reference

2020; High Grade Transformation in Mucoepidermoid Carcinoma of the Minor Salivary Gland with Polyploidy of the Rearranged MAML2 Gene
Application : IHC-P
Reactivity : Human
2019; Coping with formalin banning in pathology: under vacuum long-term tissue storage with no added formalin
Application : IHC-P
Reactivity : Human
2019; Glypican-3 and Hep Par-1 are Useful Biomarkers in the Cytologic Assessment of Ascites
Application : IHC-P
Reactivity : Human
2018; Co-localisation of Glandular and Squamous Cell Markers in Non-small Cell Lung Cancer
Application : IHC-P
Reactivity : Human
2017; Clinical and pathological characteristic of metastatic malignant mesothelioma initially diagnosed by lymph node biopsy
Application : IHC-P
Reactivity : Human
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Package List Price ($)
$ 399