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CD68 antibody [FA-11] (Biotin)

Cat. No. GTX43914

Reference 10

Host

 Rat

Clonality

 Monoclonal

Clone Name

 FA-11

Isotype

 IgG2a

Application

 ICC/IF, IHC

Reactivity

 Human, Mouse
Package
100 μg ($489)
See all CD68 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Purified Concanavalin A acceptor glycoprotein from P815 cell line.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Biotin

RRID

AB_11173719

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD68 antigen , Lamp4 , Scard1 , gp110

Database

Research Area

REFERENCE

Application Reference

Andreev D et al. Nat Commun 2024; 15 (1) : 1067 Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase.

Clone Reference

Zhang J et al. Stem Cell Res Ther 2022; 13 (1):394 Mesenchymal stem cell-derived extracellular vesicles protect retina in a mouse model of retinitis pigmentosa by anti-inflammation through miR-146a-Nr4a3 axis.
Cinato M et al. Theranostics 2021; 11 (13):6491-6506 Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling.
Gilmore AC et al. Kidney Int 2021; 99 (2):396-404 Complement activity is regulated in C3 glomerulopathy by IgG-factor H fusion proteins with and without properdin targeting domains.
Malik TH et al. Proc Natl Acad Sci U S A 2021; 118 (13) Gain-of-function factor H-related 5 protein impairs glomerular complement regulation resulting in kidney damage.
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REVIEW

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Application Reference
Andreev D et al. Nat Commun 2024; 15 (1):1067 Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase.
Andreev D et al. J Clin Invest 2020; 130 (9):4811-4830 Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin.
Clone Reference
Zhang J et al. Stem Cell Res Ther 2022; 13 (1):394 Mesenchymal stem cell-derived extracellular vesicles protect retina in a mouse model of retinitis pigmentosa by anti-inflammation through miR-146a-Nr4a3 axis.
Cinato M et al. Theranostics 2021; 11 (13):6491-6506 Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling.
Gilmore AC et al. Kidney Int 2021; 99 (2):396-404 Complement activity is regulated in C3 glomerulopathy by IgG-factor H fusion proteins with and without properdin targeting domains.
Malik TH et al. Proc Natl Acad Sci U S A 2021; 118 (13) Gain-of-function factor H-related 5 protein impairs glomerular complement regulation resulting in kidney damage.
Cianciaruso C et al. Cell Rep 2019; 27 (10):3062-3080.e11 Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Jones KI et al. EMBO Mol Med 2018; 10 (12) Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade.
Hung HS et al. PLoS One 2014; 9 (8):e104019 In vitro study of a novel nanogold-collagen composite to enhance the mesenchymal stem cell behavior for vascular regeneration.
Application : ICC/IF
Reactivity : Human
Donskow-?ysoniewska K et al. Parasite Immunol 2012; 34 (11):536-46 Heligmosmoides polygyrus fourth stages induce protection against DSS-induced colitis and change opioid expression in the intestine.
Application : IHC
Reactivity : Mouse
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 489