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CD68 antibody [KP1]

Anti-CD68 antibody [KP1] used in IHC (Paraffin sections) (IHC-P). GTX73643

Cat. No. GTX73643

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 KP1

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
1 ml ($469)
See all CD68 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Recommendations for antigen retrieval : EDTA buffer pH 8.0 at room temperature for 30 mins.
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Product Note

This antibody is specific to macrophages in a wide variety of human tissues. It reacts with myeloid precursors and peripheral blood granulocytes. It also stains a cell population known as plasmacytoid T cells.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Subcellular fraction of human alveolar macrophages.

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_375045

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD68 molecule , GP110 , LAMP4 , SCARD1

Background

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD68 antibody [KP1] used in IHC (Paraffin sections) (IHC-P). GTX73643

GTX73643 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX73643 CD68 antibody [KP1].

REFERENCE

Clone Reference

Wu Y et al. Ann Transl Med 2022; 10 (10):569 Lipid-lowering treatment in a rabbit model of atherosclerosis: a vessel wall magnetic resonance imaging study.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 469