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United States (US)

CD71 antibody [TFRC/1059]

Anti-CD71 antibody [TFRC/1059] used in Flow cytometry (FACS). GTX34548

Cat No. GTX34548

Host Mouse
Clonality Monoclonal
Clone Name TFRC/1059
Isotype IgG1
Application ICC/IF, FACS
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 1-2ug/ml
FACS Assay dependent
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Specificity/Sensitivity

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
PROPERTIES

Form

Liquid

Buffer

Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant human TFRC protein

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transferrin Receptor,Cd71,Imd46,T9,Tfr,Tfr1,Tr,Trfr,P90,Tfrc

Database

Research Area

DATA IMAGES
Anti-CD71 antibody [TFRC/1059] used in Flow cytometry (FACS). GTX34548

GTX34548 FACS Image

Flow Cytometry of human CD71 on Jurkat Cells. Black: Cells alone; Grey: Isotype Control; Green: AF488-labeled CD71 Monoclonal Antibody (TFRC/1059).