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CD71 antibody [TFRC/1817]

Anti-CD71 antibody [TFRC/1817] used in Western Blot (WB). GTX34549
Anti-CD71 antibody [TFRC/1817] used in IHC (Paraffin sections) (IHC-P). GTX34549

Cat No. GTX34549

Host Mouse
Clonality Monoclonal
Clone Name TFRC/1817
Isotype IgG2b
Application WB, ICC/IF, IHC-P
Reactivity Human
Package
100 μg ($429)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF 1-2ug/ml
IHC-P 0.5-1ug/ml for 30 minutes at RT

Note :

IHC-P
Boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes

Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Specificity/Sensitivity

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
PROPERTIES

Form

Liquid

Buffer

10mM PBS with 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml

Antigen Species

Human

Immunogen

Recombinant human TFRC protein fragment (aa94-212) (exact sequence is proprietary)

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transferrin Receptor , Cd71 , Imd46 , T9 , Tfr , Tfr1 , Tr , Trfr , P90 , Tfrc

Database

Research Area

DATA IMAGES
Anti-CD71 antibody [TFRC/1817] used in Western Blot (WB). GTX34549

GTX34549 WB Image

Western Blot Analysis of A) Jurkat (B) HeLa (C) MCF-7 & (D) K562 Cell lysate using CD71 Mouse Monoclonal Antibody (TFRC/1817).

Anti-CD71 antibody [TFRC/1817] used in IHC (Paraffin sections) (IHC-P). GTX34549

GTX34549 IHC-P Image

Formalin-fixed, paraffin-embedded Human Placenta stained with CD71 Monoclonal Antibody (TFRC/1817).

REFERENCE
There are currently no references for CD71 antibody [TFRC/1817] (GTX34549). Be the first to share your publications with this product.
REVIEW
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Package List Price ($)
$ 429