GeneTex
United States (US)

CD71 antibody [TFRC/1818]

GTX34550_20170712_IHC-P_18121410_213.jpg

Cat No. GTX34550

Host Mouse
Clonality Monoclonal
Clone Name TFRC/1818
Isotype IgG2b
Application IHC-P
Reactivity Human
APPLICATION

Application Note

IHC-P:1-2ug/ml for 30 minutes at RT.

Calculated MW

85 kDa. ( Note )

Specificity/Sensitivity

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
PROPERTIES

Form

Liquid

Buffer

Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant human TFRC protein fragment (aa94-212) (exact sequence is proprietary)

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transferrin Receptor,Cd71,Imd46,T9,Tfr,Tfr1,Tr,Trfr,P90,Tfrc

Database

Research Area

DATA IMAGES
GTX34550_20170712_IHC-P_18121410_213.jpg

GTX34550 IHC-P Image

Formalin-fixed, paraffin-embedded Human Placenta stained with CD71 Monoclonal Antibody (TFRC/1818).