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CD8 antibody [CA-8]

Anti-CD8 antibody [CA-8] used in Flow cytometry (FACS). GTX10884

Cat. No. GTX10884

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CA-8

Isotype

 IgG2a

Application

 ICC/IF, IHC-Fr, FACS

Reactivity

 Human
Package
100 μg ($449)
See all CD8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 0.5-1μg/ml
IHC-Fr 1μg/ml
FACS 1-3μg/1x10⁶cells
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites, 1.2% Sodium acetate, 2mg BSA

Preservative

0.01mg Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Human thymocytes followed by peripheral blood T cells.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD8a molecule , CD8 , Leu2 , p32

Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Database

Research Area

DATA IMAGES

Anti-CD8 antibody [CA-8] used in Flow cytometry (FACS). GTX10884

GTX10884 FACS Image

FACS analysis of human PBMC cells using GTX10884 CD8 antibody [CA-8].
Blue : Primary antibody
Green : Isotype control
Red : Cell only control
Antibody amount : 1μg/1x10⁶ cells for 30 min at 20ºC

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 449