GeneTex
United States (US)

CD8 antibody [SP16]

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Cat No. GTX16696

Host Rabbit
Clonality Monoclonal
Clone Name SP16
Isotype IgG
Application IHC-P, IHC
Reactivity Human, Mouse
APPLICATION

Application Note

IHC-P: 1/100. Retrieve antigens with 70% Formic acid for 10-30 minutes at room temperature before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user.

Positive Control

Human tonsil
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.1% Sodium Azide. Constituents: Tissue culture supernatant

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Immunogen

Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of the CD8 molecule.

Purification

Tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Cellular Localization

Cell Membrane

Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.

Research Area

DATA IMAGES
CD8-antibody-SP16_IHC_GTX16696-4_18121409_241.jpg

GTX16696 IHC Image

Human Thyroid stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-3_18121409_607.jpg

GTX16696 IHC Image

Human Prostate stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-13_18121409_139.jpg

GTX16696 IHC Image

Human Cervix stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-12_18121409_924.jpg

GTX16696 IHC Image

Human Colon stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-11_18121409_939.jpg

GTX16696 IHC Image

Human B Cell Lymphoma stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-6_18121409_558.jpg

GTX16696 IHC Image

Human Colon Adenocarcinoma stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-7_18121409_569.jpg

GTX16696 IHC Image

Human Thymus stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-9_18121409_906.jpg

GTX16696 IHC Image

Human Spleen stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-5_18121409_165.jpg

GTX16696 IHC Image

Human Esophagus stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-14_18121409_873.jpg

GTX16696 IHC Image

Human Endometrium stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-2_18121409_450.jpg

GTX16696 IHC Image

Human Fallopian Tube stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-1_18121409_482.jpg

GTX16696 IHC Image

Human Tonsil stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-10_18121409_900.jpg

GTX16696 IHC Image

Human HK Lymphoma stained with anti-CD8 antibody

CD8-antibody-SP16_IHC_GTX16696-8_18121409_667.jpg

GTX16696 IHC Image

Human Reactive Lymph Node stained with anti-CD8 antibody

REFERENCE
Package List Price ($)
$ 369