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CD89 antibody [MIP8a] (Low endotoxin, azide free)

Anti-CD89 antibody [MIP8a] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41763

Cat. No. GTX41763

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MIP8a

Isotype

 IgG1

Application

 WB, FACS, IP, ELISA, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($399)
See all CD89 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
FACS 1/50-1/100
IP Assay dependent
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.

Neutralizing/Inhibition
MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes.
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant soluble human CD89

Purification

Purified IgG

Endotoxin

< 0.01 EU/μg (determined by the LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Fc fragment of IgA receptor , CD89 , CTB-61M7.2 , FcalphaRI

Background

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD89 antibody [MIP8a] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41763

GTX41763 FACS Image

FACS analysis of human peripheral blood granulocytes using GTX41763 CD89 antibody [MIP8a] (Low endotoxin, azide free).

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations