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CDC14A antibody

Anti-CDC14A antibody used in IHC (Paraffin sections) (IHC-P). GTX52005
Anti-CDC14A antibody used in Western Blot (WB). GTX52005

Cat. No. GTX52005

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all CDC14A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-1000
IHC-P 1:50-400
Not tested in other applications.

Calculated MW

67 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human CDC14A(45-95).

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_2887785

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cell division cycle 14A , DFNB105 , DFNB32 , DFNB35 , cdc14 , hCDC14

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CDC14A antibody used in IHC (Paraffin sections) (IHC-P). GTX52005

GTX52005 IHC-P Image

IHC-P analysis of mouse testis tissue using GTX52005 CDC14A antibody.
Antigen retrieval : Boiling in sodium citrate buffer (pH6) for 15min
Dilution : 1:400

Anti-CDC14A antibody used in Western Blot (WB). GTX52005

GTX52005 WB Image

WB analysis of various samples using GTX52005 CDC14A antibody.
Dilution : 1:1000
Lane 1 : HeLa cell lysates

REFERENCE

Application Reference

Imtiaz A et al. Hum Mol Genet 2018; 27 (5) : 780-798 CDC14A phosphatase is essential for hearing and male fertility in mouse and human.
Falsetta ML et al. J Low Genit Tract Dis 2018; 22 (1) : 52-57 Toll-Like Receptor Signaling Contributes to Proinflammatory Mediator Production in Localized Provoked Vulvodynia.
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399