GeneTex
United States (US)

CDC2 antibody [POH-1]

CDC2-antibody-POH-1__GTX28040-1_18121409_571.jpg

Cat No. GTX28040

Host Mouse
Clonality Monoclonal
Clone Name POH-1
Isotype IgG2a
Application WB, ICC/IF, IHC-P, IP
Reactivity Human, Bovine, Monkey, Mink
APPLICATION

Application Note

ICC: Use at an assay dependant concentration. IHC-P: Use at an assay dependant dilution. IP: Use at an assay dependant concentration. WB: Use at an assay dependant concentration. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

34 kDa. ( Note )

Positive Control

HeLa.

Specificity/Sensitivity

Reacts with Cdc2
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline pH 7.4 containing 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cyclin Dependent Kinase 1,Cdc2,Cdc28A,P34Cdc2,Cdk1

Background

Cyclin dependent kinases are key regulators of the progression of the cell cycle. Early in the cell cycle Cdk2, Cdk4, Cdk6 and their associated cyclins regulate the G1 to S phase transition (1, 2). Cdk2 plays a key role in the G1/S and S/G2 transitions through its associations with cyclin D1, cyclin D2, cyclin D3, cyclin E and cyclin A. Cdk4 also forms complexes with the D type cyclins, and is thought to regulate cell growth through the G1 phase of the cell cycle (3-6). The late stages of the cell cycle are regulated by another cyclin dependent kinase, Cdc2 p34. This kinase exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34-cyclin B complex that is required for the G2 to M phase transition (7,8).

Database

Research Area

DATA IMAGES
CDC2-antibody-POH-1__GTX28040-1_18121409_571.jpg

GTX28040 IHC-P Image

Immunohistochemistry staining of human thymus (paraffin sections) using anti-Cdk1 (clone POH-1) (GTX28040).

Package List Price ($)
$ 319