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CDC20 antibody [CDC20/1102]

Anti-CDC20 antibody [CDC20/1102] used in IHC (Paraffin sections) (IHC-P). GTX34579
Anti-CDC20 antibody [CDC20/1102] used in IHC (Paraffin sections) (IHC-P). GTX34579

Cat No. GTX34579

Host

Mouse

Clonality

Monoclonal

Clone Name

CDC20/1102

Isotype

IgG1

Application

ICC/IF, IHC-P

Reactivity

Human
Package
100 μg ($429)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 0.5-1ug/ml
IHC-P 2-4ug/ml for 30 minutes at RT

Note :

IHC-P
Boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes

Not tested in other applications.

Calculated MW

55 kDa. ( Note )

Specificity/Sensitivity

Cyclins, regulatory subunits, which associate with kinases, control many of the important steps in cell cycle progression. The Cdc2 protein kinase (p34Cdc2) exhibits protein kinase activity in vitro and exists in a complex with both cyclin B and a protein homologous to p13SUC1. Cdc2 kinase is the active subunit of the M phase promoting factor (MPF) and the M phase-specific Histone H1 kinase. The p34Cdc2/cyclin B complex is required for the G2 to M transition. An additional cell cycle-dependent protein kinase, termed p55cdc, exhibits a high degree of homology with the S. cerevisiae proteins Cdc20 and Cdc4. The p55cdc transcript is readily detectable in a variety of cultured cell lines in growth phase, but disappears when cell growth is chemically arrested.

PROPERTIES

Form

Liquid

Buffer

10mM PBS with 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml

Antigen Species

Human

Immunogen

Recombinant human Cdc20 protein

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Cell Division Cycle 20 , Cdc20A , Ba276H19.3 , P55Cdc , Cdc20

Background

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CDC20 antibody [CDC20/1102] used in IHC (Paraffin sections) (IHC-P). GTX34579

GTX34579 IHC-P Image

Formalin-fixed, paraffin-embedded human Tonsil stained with CDC20 Monoclonal Antibody (CDC20/1102)

Anti-CDC20 antibody [CDC20/1102] used in IHC (Paraffin sections) (IHC-P). GTX34579

GTX34579 IHC-P Image

Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with CDC20 Monoclonal Antibody (CDC20/1102)

REFERENCE

There are currently no references for CDC20 antibody [CDC20/1102] (GTX34579). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CDC20 antibody [CDC20/1102] (GTX34579). Be the first to share your experience with this product.
Package List Price ($)
$ 429