GeneTex
United States (US)

CDC23 antibody

GTX17066_2349_WB_20180221_18121410_786.jpg
GTX17066_47_ICC-IF_20180221_18121410_565.jpg

Cat No. GTX17066

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

69 kDa. ( Note )

Positive Control

K-562 Cell Slide(GTX25535) , K562 Cell Lysate(GTX27911)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CDC23 antibody was raised against a 17 amino acid synthetic peptide near the center of human CDC23.The immunogen is located within amino acids 270 - 320 of CDC23.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cell Division Cycle 23,Anapc8,Apc8,Cut23,Cdc23

Background

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX17066_2349_WB_20180221_18121410_786.jpg

GTX17066 WB Image

WB analysis of K562 cell lysate using GTX17066 CDC23 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

GTX17066_47_ICC-IF_20180221_18121410_565.jpg

GTX17066 ICC/IF Image

ICC/IF analysis of K562 cells using GTX17066 CDC23 antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329