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CDC6 (phospho Ser54) antibody

Anti-CDC6 (phospho Ser54) antibody used in Western Blot (WB). GTX55007
Anti-CDC6 (phospho Ser54) antibody used in IHC (Paraffin sections) (IHC-P). GTX55007

Cat. No. GTX55007

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all CDC6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

63 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of CDC6. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cell division cycle 6 , CDC18L , HsCDC18 , HsCDC6 , MGORS5

Cellular Localization

Nucleus,Cytoplasm

Background

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CDC6 (phospho Ser54) antibody used in Western Blot (WB). GTX55007

GTX55007 WB Image

WB analysis of serum starvation-treated HeLa (A), serum starvation-treated Raw264.7 (B), serum starvation-treated H9C2 (C) whole cell lysates using GTX55007 CDC6 (phospho Ser54) antibody.

Anti-CDC6 (phospho Ser54) antibody used in IHC (Paraffin sections) (IHC-P). GTX55007

GTX55007 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX55007 CDC6 (phospho Ser54) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399