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CDC7 antibody

Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149
Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149
Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149
Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149
Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149

Cat. No. GTX78149

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
25 μg ($299)
See all CDC7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 5.2 μg/ml
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

Predict Reactivity

Gibbon, Gorilla(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 19 amino acid peptide from kinase domain of human CDC7.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_425097

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cell division cycle 7 , CDC7 , CDC7L1 , HsCDC7 , Hsk1 , huCDC7

Cellular Localization

Nucleus

Background

This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149

GTX78149 IHC-P Image

IHC-P analysis of human prostate, carcinoma tissue using GTX78149 CDC7 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149

GTX78149 IHC-P Image

IHC-P analysis of brain, alzheimer's neurofibrillary tangle and granulovacuolar degeneration tissue using GTX78149 CDC7 antibody.

Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149

GTX78149 IHC-P Image

IHC-P analysis of colon, adenocarcinoma tissue using GTX78149 CDC7 antibody.

Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149

GTX78149 IHC-P Image

IHC-P analysis of human ovary, carcinoma tissue using GTX78149 CDC7 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-CDC7 antibody used in IHC (Paraffin sections) (IHC-P). GTX78149

GTX78149 IHC-P Image

IHC-P analysis of human testis tissue using GTX78149 CDC7 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

Application Reference

Gad SA et al. Sci Rep 2019; 9 (1) : 14197 Targeting CDC7 sensitizes resistance melanoma cells to BRAFV600E-specific inhibitor by blocking the CDC7/MCM2-7 pathway.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299