APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 |
1:50-1:100 |
1:10-1:50 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rat(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide between 99-125 amino acids from the Central region of human CDIPT.
Purification
Protein A purified, followed by peptide affinity purification.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CDP-diacylglycerol--inositol 3-phosphatidyltransferase , PIS , PIS1
Cellular Localization
Endoplasmic reticulum membrane,Golgi apparatus membrane,Cell membrane,Membrane
Background
Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Database
Research Area
DATA IMAGES
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GTX80599 IHC-P Image
IHC-P analysis of human brain tissue using GTX80599 CDIPT antibody, Internal.
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GTX80599 WB Image
WB analysis of mouse stomach tissue lysate (35ug/lane) using GTX80599 CDIPT antibody, Internal.
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GTX80599 FACS Image
FACS analysis of MCF-7 cells using GTX80599 CDIPT antibody, Internal. Top histogram : negative control Bottom histogram : MCF-7 cells
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REFERENCE
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REVIEW
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