CDK5 antibody [4E4]

Cat. No. GTX60441

Host	Mouse
Clonality	Monoclonal
Clone Name	4E4
Isotype	IgG1
Application	WB, ICC/IF, IHC-P, FACS, ELISA
Reactivity	Human, Rat, Monkey
Package	100 μl ($409)

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Datasheet
Document

View product citations for antibody GTX60441 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1/500 - 1/2000
ICC/IF	1/200 - 1/1000
IHC-P	1/200 - 1/1000
FACS	1/200 - 1/400
ELISA	1/10000

Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human CDK5 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cyclin dependent kinase 5 , LIS7 , PSSALRE

Background

This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Database

Gene ID: 1020 CDK5
UniProt: Q00535 CDK5

Research Area

DATA IMAGES

GTX60441 ELISA Image

ELISA analysis of antigen using GTX60441 CDK5 antibody [4E4].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng

GTX60441 FACS Image

FACS analysis of K562 cells using GTX60441 CDK5 antibody [4E4].
Green : CDK5
Purple : negative control

GTX60441 IHC-P Image

IHC-P analysis of human cerebellum tissue (left) and brain tissue (right) using GTX60441 CDK5 antibody [4E4].

GTX60441 ICC/IF Image

ICC/IF analysis of GC7901 cells using GTX60441 CDK5 antibody [4E4].
Green : CDK5
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments

GTX60441 WB Image

WB analysis of HeLa (1), K562 (2), PC-12 (3) and Cos7 (4) cell lysate using GTX60441 CDK5 antibody [4E4].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf

Package

List Price ($)

100 μl

$ 409

Qty