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CDK6 antibody

Anti-CDK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX33085
Anti-CDK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX33085
Anti-CDK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX33085
Anti-CDK6 antibody used in Western Blot (WB). GTX33085

Cat. No. GTX33085

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all CDK6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein of human CDK6

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cyclin dependent kinase 6 , MCPH12 , PLSTIRE

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-CDK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX33085

GTX33085 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX33085 CDK6 antibody.
Dilution : 1:200

Anti-CDK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX33085

GTX33085 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX33085 CDK6 antibody.
Dilution : 1:100

Anti-CDK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX33085

GTX33085 IHC-P Image

IHC-P analysis of rat lung tissue using GTX33085 CDK6 antibody.
Dilution : 1:100

Anti-CDK6 antibody used in Western Blot (WB). GTX33085

GTX33085 WB Image

WB analysis of various sample lysates using GTX33085 CDK6 antibody.
Dilution : 1:300
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399