GeneTex
United States (US)

CDK6 antibody

GTX33085_20180530_IHC-P_1_18121410_783.jpg
GTX33085_20180530_WB_18121410_350.jpg
GTX33085_20180530_IHC-P_18121410_234.jpg
GTX33085_20180530_IHC-P_2_18121410_150.jpg

Cat No. GTX33085

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

37 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant protein of human CDK6

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cyclin Dependent Kinase 6,Mcph12,Plstire,Cdk6

Background

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES
GTX33085_20180530_IHC-P_1_18121410_783.jpg

GTX33085 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX33085 CDK6 antibody.
Dilution : 1:200

GTX33085_20180530_WB_18121410_350.jpg

GTX33085 WB Image

WB analysis of various samples using GTX33085 CDK6 antibody.
Dilution : 1:300
Loading : 25μg per lane

GTX33085_20180530_IHC-P_18121410_234.jpg

GTX33085 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX33085 CDK6 antibody.
Dilution : 1:100

GTX33085_20180530_IHC-P_2_18121410_150.jpg

GTX33085 IHC-P Image

IHC-P analysis of rat lung tissue using GTX33085 CDK6 antibody.
Dilution : 1:100

Package List Price ($)
$ 329