GeneTex
United States (US)

CDK9 antibody

Cat No. GTX10874

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IP, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/500-1/3,000
IHC-P 1/200-1/1,000
IP Assay dependent
ELISA 1/10,000-1/50,000
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Specificity/Sensitivity

This antibody does not cross react with other cyclin dependent kinases.
PROPERTIES

Form

Liquid

Buffer

PBS, 0.01% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Multiple synthetic peptides corresponding to the C-terminal and N-terminal domains of human CDK9

Purification

Serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cyclin Dependent Kinase 9,C-2K,Cdc2L4,Ctk1,Pitalre,Tak,Cdk9

Background

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]

Database

Research Area

Package List Price ($)
$ 339