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CDX2 antibody [CDX2/1690]

Anti-CDX2 antibody [CDX2/1690] used in Protein Array (Protein Array). GTX34585
Anti-CDX2 antibody [CDX2/1690] used in IHC (Paraffin sections) (IHC-P). GTX34585
Anti-CDX2 antibody [CDX2/1690] used in IHC (Paraffin sections) (IHC-P). GTX34585

Cat No. GTX34585

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CDX2/1690

Isotype

 IgG2a

Application

 IHC-P, ELISA, Protein Array

Reactivity

 Human
Package
100 μg ($339)
See all CDX2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1-2μg/ml for 30 min at RT
ELISA 2-4μg/ml (for coating)
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% sodium azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa150-249) of human CDX2 protein (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CDX2 , CDX2/AS , CDX3 , caudal type homeobox 2

Cellular Localization

Nucleus

Background

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]

Database

Research Area

DATA IMAGES

Anti-CDX2 antibody [CDX2/1690] used in Protein Array (Protein Array). GTX34585

GTX34585 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using CDX2 Mouse Monoclonal Antibody (CDX2/1690). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-CDX2 antibody [CDX2/1690] used in IHC (Paraffin sections) (IHC-P). GTX34585

GTX34585 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX34585 CDX2 antibody [CDX2/1690].

Anti-CDX2 antibody [CDX2/1690] used in IHC (Paraffin sections) (IHC-P). GTX34585

GTX34585 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX34585 CDX2 antibody [CDX2/1690].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339